Speaking of Frank Luntz (see comments on this thread: I'm Not Interested in Finding a Truce in the Culture War. I'm Interested in Winning It. )
There were numerous contentious moments in Bill Maher's "Real Time" interview with conservative pollster Frank Luntz, but perhaps the most compelling was an off-the-cuff response to Luntz's congratulating the host on being renewed for two more seasons.
After remarking on the renewal, Luntz quipped, "You should be a Republican."
Maher's response is absolutely priceless. Watch the full interview above; this particular exchange takes place starting at about 4:30.